A plant-based diet is increasingly becoming recognized as a healthier alternative to a diet laden with meat. Atherosclerosis associated with high dietary intake of meat, fat, and carbohydrates remains the leading cause of mortality in the US. This condition results from progressive damage to the endothelial cells lining the vascular system, including the heart, leading to endothelial dysfunction. In addition to genetic factors associated with endothelial dysfunction, many dietary and other lifestyle factors, such as tobacco use, high meat and fat intake, and oxidative stress, are implicated in atherogenesis. Polyphenols derived from dietary plant intake have protective effects on vascular endothelial cells, possibly as antioxidants that prevent the oxidation of low-density lipoprotein. Recently, metabolites of L-carnitine, such as trimethylamine-N-oxide, that result from ingestion of red meat have been identified as a potential predictive marker of coronary artery disease CAD. Metabolism of L-carnitine by the intestinal microbiome is associated with atherosclerosis in omnivores but not in vegetarians, supporting CAD benefits of a plant-based diet. Trimethylamine-N-oxide may cause atherosclerosis via macrophage activation. We suggest that a shift toward a plant-based diet may confer protective effects against atherosclerotic CAD by increasing endothelial protective factors in the circulation while reducing factors that are injurious to endothelial cells.
Evidence supporting the role of nutrition in heart failure HF incidence and severity is growing. A comprehensive search of online databases was conducted using relevant keywords to identify human studies including diet and HF. Several other plant-based dietary patterns, including low-fat diets and the rice diet, also show promise. Higher dietary quality, as assessed using different scores, seems to provide protective qualities. Some evidence suggests detrimental effects of dairy products and poultry, but more research is needed. Potential mechanisms for this include decreased oxidative stress, homocysteine and inflammation levels, as well as higher antioxidant defence and nitric oxide bioavailability with gut microbiome modulation. Well-designed randomised, controlled nutrition intervention trials specific to HF are urgently required. Heart failure HF is a major cause of hospitalisation, morbidity and mortality. Most research into HF has focused on pharmacology and devices, with little attention being paid to nutrition. As nutritional modification is relatively low risk and low cost option, it is an attractive strategy for reducing HF incidence and severity. This review briefly summarises the evidence of the impact of dietary pattern on HF incidence and severity.
A preliminary intervention trial with participants, published in , suggested a natriuretic action of the DASH diet, in conjunction with a hypotensive effect. Diabetes Care. Hypertension is defined as a systolic pressure of mmHg or more, or a diastolic pressure of 90 mmHg or more. You don’t need to go full vegetarian or vegan avoiding all animal products, even eggs and dairy to get the best heart health benefits. Evidence supporting the role of nutrition in heart failure HF incidence and severity is growing. Folate and B6 are available in yeast extract, green leafy vegetables, pulses peas, beans, lentils, wholegrains wholemeal bread, wholemeal pasta, brown rice, oats, nuts and fortified breakfast cereals. Another potential mechanism of action is dietary modulation of the gut microbiome. When it comes to your heart, are all animal foods off the table? After a year, even severely blocked arteries had reopened. The heart and the blood vessels arteries, veins and capillaries make up our circulatory system called the cardiovascular system.