Background: Multiple diet indexes have been developed to capture the Dietary Approaches to Stop Hypertension DASH dietary pattern and examine relations with health outcomes but have not been compared within the same study population to our knowledge. Results: From through , incident colorectal cancer cases were ascertained. In men, higher scores were associated with reduced colorectal cancer incidence by comparing highest to lowest quintiles for all indexes as follows: Dixon HR: 0. Higher scores in women were inversely associated with colorectal cancer incidence by using methods defined by Mellen HR: 0. Conclusion: The consistency in findings, particularly in men, suggests that all indexes capture an underlying construct inherent in the DASH dietary pattern, although the specific index used can affect results. Epidemiologic studies have traditionally assessed effects of single nutrients, foods, and other individual dietary constituents on cancer risk. Research that has used this approach is valuable for understanding potential biological mechanisms that underlie observed associations, but it has been limited by the multicollinearity of dietary intake variables and the inability to detect small effects of single dietary components 1. The investigation of dietary patterns or overall diet quality is a promising complementary approach to help overcome some of these limitations 1 — 4 and provide useful information for developing guidelines and public health recommendations. National and international cancer organizations have recommend a largely plant-based dietary pattern that is rich in fruits, vegetables, whole grains, and legumes and low in red and processed meat, refined grains, added sugar, and energy density for cancer prevention 5. The Dietary Guidelines for Americans also provided similar recommendations based on dietary patterns, with the addition of low-fat dairy products, to promote health and reduce risk of chronic disease, including cancer. The first DASH trial showed that a diet rich in fruit, vegetables, and low-fat dairy products and reduced in saturated and total fat labeled the DASH diet significantly reduced blood pressure 6.
Metrics details. Although previous investigations have proposed an association between Dietary Approaches to Stop Hypertension DASH -style diet and lower mortality from chronic diseases, the exposure-response relationship is not clear. The present systematic review and meta-analysis aimed to explore the linear and non-linear dose-response association between adherence to the DASH diet and all-cause and cause-specific mortality. The two-stage hierarchical regression model was applied to test the potential non-linear dose-response associations. The inclusion criteria were met by 17 studies 13 publications. The scores reported for adherence to the DASH diet in different studies were converted to a conventional scoring method in which the adherence score might range between 8 to The linear analysis revealed that summary HRs were 0. Even the modest adherence to the DASH diet is associated with a lower risk of all-cause and cause-specific mortality.
Results: From through , incident colorectal cancer cases were ascertained. As shown in Table 4, in the model adjusted for age and energy intake, incidence of hypertension was inversely associated with the degree of concordance with the DASH diet, with hazard ratios across categories of 1. Stata J. A total of 4. Susan M Krebs-Smith. Metrics details.