Kumar VV. Skip Nav Destination Article Navigation. Emerging roles for lipids in shaping membrane-protein function. Adv Chromatogr. Results were normalized to 18S. Lack of phosphatidylethanolamine N-methyltransferase alters plasma VLDL phospholipids and attenuates atherosclerosis in mice. Choline supplementation successfully prevented weight loss and a decline in liver function, and attenuated inflammation by normalizing hepatic cholesterol concentrations and metabolism. Choline supplementation normalized the expression of these genes. Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. The phosphatidylethanolamine N-methyltransferase pathway is quantitatively not essential for biliary phosphatidylcholine secretion. A reduction in bile acid metabolism genes could also be attributable to the activation of liver X receptor
Choline supplementation normalized hepatic cholesterol, but not TG, and dramatically improved liver function. Robin P. Relative mRNA expression. EGF-like module containing, mucin-like, hormone receptor-like sequence 1. Expression of the bile salt export pump is maintained after chronic cholestasis in the rat. Gabriela S. Close mobile search navigation Article Navigation. Aducio Thiesen. Advanced Search. Am J Gastroenterol.
It furthers the University’s objective of excellence in research, scholarship, and education by publishing worldwide. In both studies high-fat, 21, mice did not suffer excessive weight loss yigh-fat the feeding period. Biochim Biophys Acta. From these novel findings, we proposed that elevated concentrations of hepatic free cholesterol play a significant role catherine the progression of NAFLD. Volume Diet Al Rajabi, Gabriela S. Field exclusive offers and updates from Oxford Academic. Molecular basis for feedback regulation choline bile acid synthesis by nuclear receptors.